BMRB: 17987

New tricks of an old fold: structural versatility of scorpion toxins with common cysteine spacing

Authors

del Rio-Portilla, F., Saucedo, A.L., Flores-Solis, D.

Assembly

Ts16

Entity

1. Ts16 (polymer), 31 monomers, 3453.072 Da Detail

GSGCMKEYCA GQCRGKVSQD YCLKHCKCIP R

Formula weight

3453.072 Da

Source organism

Tityus serrulatus

Exptl. method

solution NMR

Refine. method

simulated annealing

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 96.2 %, Completeness (bb): 96.9 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	96.2 % (179 of 186)	96.2 % (179 of 186)
Backbone	96.9 % (63 of 65)	96.9 % (63 of 65)
Sidechain	95.9 % (116 of 121)	95.9 % (116 of 121)
Aromatic	100.0 % (10 of 10)	100.0 % (10 of 10)
Methyl	100.0 % (7 of 7)	100.0 % (7 of 7)

1. Ts16

GSGCMKEYCA GQCRGKVSQD YCLKHCKCIP R

Show sample condition

Sample

Solvent system 95% H2O, 5% D2O ), Pressure 1 atm, Temperature 298 K, pH 3.5, Details buffer NA

#	Name	Isotope labeling	Type	Concentration
1	Ts16	natural abundance		1.4 mM
2	H2O	natural abundance		95 %
3	D2O	natural abundance		5 %

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Protein Blocks Logo

Calculated from 20 models in PDB: 2LO7, Strand ID: A Detail

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Release date

2012-01-17

Citation

New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing
Saucedo, A., Flores-Solis, D., Rodriguez de la Vega, R.C., Ramirez-Cordero, B., Hernandez-Lopez, R., Cano-Sanchez, P., Noriega Navarro, R., Garcia-Valdes, J., Coronas-Valderrama, F., de Roodt, A., Brieba, L.G., Domingos Possani, L., del Rio-Portilla, F.
J. Biol. Chem. (2012), 287, 12321-12330, PubMed 22238341 , DOI 10.1074/jbc.M111.329607 , Abstract

Entries sharing articles BMRB: 1, Swiss-Prot: 2 entries Detail

Related entities 1. Ts16, : 1 : 1 : 7 entities Detail

Experiments performed 4 experiments Detail