BMRB: 17464

Solution Structure of Acidic Fibroblast Growth Factor Bound to 1,3,6-Naphthalenetrisulfonate: A Minimal Model for the Anti-tumoral Action of Suramins and Suradistas

Authors

Lozano, R.M., Jimenez, M.A., Santoro, J., Rico, M., Gimenez-Gallego, G.

Assembly

FGF/NTS complex

Entity

1. FGF (polymer, Thiol state: not reported), 132 monomers, 14932.68 Da Detail

KKPKLLYCSN GGHFLRILPD GTVDGTRDRS DQHIQLQLSA ESVGEVYIKS TETGQYLAMD TDGLLYGSQT PNEECLFLER LEENHYNTYI SKKHAEKNWF VGLKKNGSCK RGPRTHYGQK AILFLPLPVS SD

2. NTS (non-polymer, Thiol state: not present), 365.336 Da

Total weight

15298.016 Da

Max. entity weight

14932.68 Da

Source organism

Homo sapiens

Exptl. method

solution NMR

Data set

chemical_rates

Chemical rate

1 kex values in 1 lists
Pressure 1 atm, Temperature 298 K, pH 6.0 Detail

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List #1 Chemical_rate_list

Obs. entity ID	Value type	Value	Value error	Value min	Value max
1	kex	10 s-1

Release date

2012-06-05

Citation

Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas
Lozano, R.M., Jimenez, M.A., Santoro, J., Rico, M., Gimenez-Gallego, G.
J. Mol. Biol. (1998), 281, 899-915, PubMed 9719643 , DOI: , Abstract

Entries sharing articles BMRB: 1, Swiss-Prot: 1 entries Detail

Related entities 1. FGF, : 1 : 25 : 7 : 52 : 188 entities Detail

Interaction partners 1. FGF, : 9 interactors Detail

Experiments performed 1 experiments Detail