Search

Query history

Search help 
Download

Found 1 Document (1.083 seconds)

BMRB: 34723

Structure of a hybrid-type G-quadruplex with a snapback loop and an all-syn G-column (hybrid-1R)
Authors
Jana, J., Vianney, Y.M., Schroeder, N., Weisz, K.
Assembly
DNA (5'-D(*(DG5)P*(BGM)P*CP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
Entity
1. DNA (5'-D(*(DG5)P*(BGM)P*CP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3') (polymer, Thiol state: not present), 20 monomers, 6388.948 Da Detail

XXCTAGGGTG GGTGGGTCAG


Formula weight
6388.948 Da
Source organism
synthetic construct
Exptl. method
solution NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 90.0 %, Completeness: 63.5 %, Completeness (bb): 57.1 % Detail
Download

Polymer type: polydeoxyribonucleotide

Total1H
All63.5 % (108 of 170)63.5 % (108 of 170)
Suger, PO457.1 % (72 of 126)57.1 % (72 of 126)
Nucleobase81.8 % (36 of 44)81.8 % (36 of 44)
Aromatic88.9 % (32 of 36)88.9 % (32 of 36)
Methyl100.0 % (4 of 4)100.0 % (4 of 4)

1. entity 1

XXCTAGGGTG GGTGGGTCAG

Show sample condition
Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 303 K, pH 7.0, Details 0.3 mM DNA, 90% H2O/10% D2O


#NameIsotope labelingTypeConcentration
1DNAnatural abundance0.3 mM

Release date
2022-04-26
Citation
Guiding the folding of G-quadruplexes through loop residue interactions
Jana, J., Vianney, Y.M., Schroeder, N., Weisz, K.
Nucleic Acids Res. (2022), 50, 7161-7175, PubMed 35758626 , DOI 10.1093/nar/gkac549 ,
Entries sharing articles BMRB: 2 entries Detail
  BMRB: 34721 released on 2022-04-26
    Title Structure of a hybrid-type G-quadruplex with a snapback loop (hybrid 1R')
  BMRB: 34722 released on 2022-04-26
    Title Structure of a parallel G-quadruplex with a snapback loop
Experiments performed 3 experiments Detail
Chemical shift validation 3 contents Detail
Keywords DNA, hybrid G-quadruplex, snapback loop