BMRBj - BMREntryMaster

Found 1 Document (0.825 seconds)

BMRB: 34795

8CJT

JzTx-34 toxin peptide W33A mutant

Authors

Landon, C., Meudal, H.

Assembly

Mu-theraphotoxin-Cg1a

Entity

1. Mu-theraphotoxin-Cg1a (polymer, Thiol state: all disulfide bound), 35 monomers, 4041.617 Da Detail

ACREWLGGCS KDADCCAHLE CRKKWPYHCV WDATV

Formula weight

4041.617 Da

Entity Connection

disulfide 3 Detail

ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS2:SG	1:CYS16:SG
2	disulfide	sing	1:CYS9:SG	1:CYS21:SG
3	disulfide	sing	1:CYS15:SG	1:CYS29:SG

Source organism

Chilobrachys

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 228 assignments Detail

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Ambig. code
1	1	1	ALA	HA	H	4.172	1
2	1	1	ALA	HB1	H	1.576	1
3	1	1	ALA	HB2	H	1.576	1
4	1	1	ALA	HB3	H	1.576	1
5	1	2	CYS	H	H	8.607	1
6	1	2	CYS	HA	H	4.687	1
7	1	2	CYS	HB2	H	3.148	1
8	1	2	CYS	HB3	H	2.830	1
9	1	3	ARG	H	H	9.212	1
10	1	3	ARG	HA	H	4.456	1
11	1	3	ARG	HB2	H	1.670	1
12	1	3	ARG	HB3	H	1.975	1
13	1	3	ARG	HG2	H	1.780	1
14	1	3	ARG	HG3	H	2.057	1
15	1	3	ARG	HD2	H	3.269	1
16	1	3	ARG	HD3	H	3.269	1
17	1	3	ARG	HE	H	7.262	1
18	1	4	GLU	H	H	8.346	1
19	1	4	GLU	HA	H	4.076	1
20	1	4	GLU	HB2	H	2.317	1
21	1	4	GLU	HB3	H	1.898	1
22	1	4	GLU	HG2	H	2.444	1
23	1	4	GLU	HG3	H	2.319	1
24	1	5	TRP	H	H	8.142	1
25	1	5	TRP	HA	H	3.596	1
26	1	5	TRP	HB2	H	3.074	1
27	1	5	TRP	HB3	H	2.616	1
28	1	5	TRP	HD1	H	6.510	1
29	1	5	TRP	HE1	H	10.437	1
30	1	5	TRP	HE3	H	7.549	1
31	1	5	TRP	HZ2	H	7.585	1
32	1	5	TRP	HZ3	H	7.190	1
33	1	5	TRP	HH2	H	7.288	1
34	1	6	LEU	H	H	8.563	1
35	1	6	LEU	HA	H	3.029	1
36	1	6	LEU	HB2	H	1.491	1
37	1	6	LEU	HB3	H	0.908	1
38	1	6	LEU	HG	H	-0.100	1
39	1	6	LEU	HD11	H	-0.492	1
40	1	6	LEU	HD12	H	-0.492	1
41	1	6	LEU	HD13	H	-0.492	1
42	1	6	LEU	HD21	H	-0.115	1
43	1	6	LEU	HD22	H	-0.115	1
44	1	6	LEU	HD23	H	-0.115	1
45	1	7	GLY	H	H	9.016	1
46	1	7	GLY	HA2	H	4.030	1
47	1	7	GLY	HA3	H	3.425	1
48	1	8	GLY	H	H	8.568	1
49	1	8	GLY	HA2	H	3.752	1
50	1	8	GLY	HA3	H	4.239	1
51	1	9	CYS	H	H	7.569	1
52	1	9	CYS	HA	H	4.948	1
53	1	9	CYS	HB2	H	3.232	1
54	1	9	CYS	HB3	H	3.232	1
55	1	10	SER	H	H	9.614	1
56	1	10	SER	HA	H	4.625	1
57	1	10	SER	HB2	H	3.864	1
58	1	10	SER	HB3	H	3.828	1
59	1	11	LYS	H	H	7.998	1
60	1	11	LYS	HA	H	4.659	1
61	1	11	LYS	HB2	H	1.992	1
62	1	11	LYS	HB3	H	1.869	1
63	1	11	LYS	HG2	H	1.463	1
64	1	11	LYS	HG3	H	1.048	1
65	1	11	LYS	HD2	H	1.692	1
66	1	11	LYS	HD3	H	1.605	1
67	1	11	LYS	HE2	H	2.985	1
68	1	11	LYS	HE3	H	2.864	1
69	1	12	ASP	H	H	9.007	1
70	1	12	ASP	HA	H	4.135	1
71	1	12	ASP	HB2	H	2.633	1
72	1	12	ASP	HB3	H	2.927	1
73	1	13	ALA	H	H	8.302	1
74	1	13	ALA	HA	H	4.234	1
75	1	13	ALA	HB1	H	1.382	1
76	1	13	ALA	HB2	H	1.382	1
77	1	13	ALA	HB3	H	1.382	1
78	1	14	ASP	H	H	8.028	1
79	1	14	ASP	HA	H	5.075	1
80	1	14	ASP	HB2	H	2.829	1
81	1	14	ASP	HB3	H	3.198	1
82	1	15	CYS	H	H	7.695	1
83	1	15	CYS	HA	H	4.456	1
84	1	15	CYS	HB2	H	2.838	1
85	1	15	CYS	HB3	H	3.020	1
86	1	16	CYS	H	H	9.059	1
87	1	16	CYS	HA	H	4.629	1
88	1	16	CYS	HB2	H	2.557	1
89	1	16	CYS	HB3	H	3.517	1
90	1	17	ALA	H	H	7.849	1
91	1	17	ALA	HA	H	4.023	1
92	1	17	ALA	HB1	H	1.166	1
93	1	17	ALA	HB2	H	1.166	1
94	1	17	ALA	HB3	H	1.166	1
95	1	18	HIS	H	H	8.564	1
96	1	18	HIS	HA	H	4.309	1
97	1	18	HIS	HB2	H	3.945	1
98	1	18	HIS	HB3	H	3.657	1
99	1	18	HIS	HD2	H	7.229	1
100	1	18	HIS	HE1	H	8.603	1
101	1	19	LEU	H	H	7.715	1
102	1	19	LEU	HA	H	5.217	1
103	1	19	LEU	HB2	H	1.062	1
104	1	19	LEU	HB3	H	2.221	1
105	1	19	LEU	HG	H	1.311	1
106	1	19	LEU	HD11	H	0.627	1
107	1	19	LEU	HD12	H	0.627	1
108	1	19	LEU	HD13	H	0.627	1
109	1	19	LEU	HD21	H	-0.234	1
110	1	19	LEU	HD22	H	-0.234	1
111	1	19	LEU	HD23	H	-0.234	1
112	1	20	GLU	H	H	9.452	1
113	1	20	GLU	HA	H	4.526	1
114	1	20	GLU	HB2	H	1.954	1
115	1	20	GLU	HB3	H	1.954	1
116	1	20	GLU	HG2	H	1.956	1
117	1	20	GLU	HG3	H	2.103	1
118	1	21	CYS	H	H	9.535	1
119	1	21	CYS	HA	H	4.713	1
120	1	21	CYS	HB2	H	2.674	1
121	1	21	CYS	HB3	H	2.575	1
122	1	22	ARG	H	H	8.087	1
123	1	22	ARG	HA	H	4.096	1
124	1	22	ARG	HB2	H	2.004	1
125	1	22	ARG	HB3	H	1.865	1
126	1	22	ARG	HG2	H	1.788	1
127	1	22	ARG	HG3	H	1.745	1
128	1	22	ARG	HD2	H	3.171	1
129	1	22	ARG	HD3	H	2.868	1
130	1	22	ARG	HE	H	7.064	1
131	1	23	LYS	H	H	8.452	1
132	1	23	LYS	HA	H	3.996	1
133	1	23	LYS	HB2	H	1.630	1
134	1	23	LYS	HB3	H	1.854	1
135	1	23	LYS	HG2	H	1.257	1
136	1	23	LYS	HG3	H	1.257	1
137	1	23	LYS	HD2	H	1.474	1
138	1	23	LYS	HD3	H	1.474	1
139	1	23	LYS	HE2	H	2.948	1
140	1	23	LYS	HE3	H	2.948	1
141	1	24	LYS	H	H	7.285	1
142	1	24	LYS	HA	H	4.566	1
143	1	24	LYS	HB2	H	1.708	1
144	1	24	LYS	HB3	H	1.568	1
145	1	24	LYS	HG2	H	1.382	1
146	1	24	LYS	HG3	H	1.382	1
147	1	24	LYS	HD2	H	1.705	1
148	1	24	LYS	HD3	H	1.703	1
149	1	24	LYS	HE2	H	3.011	1
150	1	24	LYS	HE3	H	3.011	1
151	1	25	TRP	H	H	8.610	1
152	1	25	TRP	HA	H	3.463	1
153	1	25	TRP	HB2	H	3.056	1
154	1	25	TRP	HB3	H	3.059	1
155	1	25	TRP	HD1	H	7.124	1
156	1	25	TRP	HE1	H	10.180	1
157	1	25	TRP	HE3	H	7.164	1
158	1	25	TRP	HZ2	H	7.474	1
159	1	25	TRP	HZ3	H	7.067	1
160	1	25	TRP	HH2	H	7.207	1
161	1	26	PRO	HA	H	2.799	1
162	1	26	PRO	HB2	H	1.234	1
163	1	26	PRO	HB3	H	0.800	1
164	1	26	PRO	HG2	H	1.382	1
165	1	26	PRO	HG3	H	1.113	1
166	1	26	PRO	HD2	H	2.980	1
167	1	26	PRO	HD3	H	3.232	1
168	1	27	TYR	H	H	7.670	1
169	1	27	TYR	HA	H	4.401	1
170	1	27	TYR	HB2	H	3.158	1
171	1	27	TYR	HB3	H	3.207	1
172	1	27	TYR	HD1	H	7.157	1
173	1	27	TYR	HD2	H	7.157	1
174	1	27	TYR	HE1	H	6.855	1
175	1	27	TYR	HE2	H	6.855	1
176	1	28	HIS	H	H	7.047	1
177	1	28	HIS	HA	H	5.483	1
178	1	28	HIS	HB2	H	2.544	1
179	1	28	HIS	HB3	H	2.849	1
180	1	28	HIS	HD2	H	6.595	1
181	1	28	HIS	HE1	H	8.126	1
182	1	29	CYS	H	H	9.013	1
183	1	29	CYS	HA	H	5.102	1
184	1	29	CYS	HB2	H	2.719	1
185	1	29	CYS	HB3	H	2.957	1
186	1	30	VAL	H	H	9.773	1
187	1	30	VAL	HA	H	4.790	1
188	1	30	VAL	HB	H	2.562	1
189	1	30	VAL	HG11	H	1.006	1
190	1	30	VAL	HG12	H	1.006	1
191	1	30	VAL	HG13	H	1.006	1
192	1	30	VAL	HG21	H	0.907	1
193	1	30	VAL	HG22	H	0.907	1
194	1	30	VAL	HG23	H	0.907	1
195	1	31	TRP	H	H	7.552	1
196	1	31	TRP	HA	H	5.014	1
197	1	31	TRP	HB2	H	3.512	1
198	1	31	TRP	HB3	H	3.074	1
199	1	31	TRP	HD1	H	7.019	1
200	1	31	TRP	HE1	H	8.394	1
201	1	31	TRP	HE3	H	7.824	1
202	1	31	TRP	HZ2	H	7.021	1
203	1	31	TRP	HZ3	H	7.075	1
204	1	31	TRP	HH2	H	7.130	1
205	1	32	ASP	H	H	8.695	1
206	1	32	ASP	HA	H	4.574	1
207	1	32	ASP	HB2	H	2.952	1
208	1	32	ASP	HB3	H	2.489	1
209	1	33	ALA	H	H	8.272	1
210	1	33	ALA	HA	H	4.357	1
211	1	33	ALA	HB1	H	1.451	1
212	1	33	ALA	HB2	H	1.451	1
213	1	33	ALA	HB3	H	1.451	1
214	1	34	THR	H	H	8.565	1
215	1	34	THR	HA	H	4.314	1
216	1	34	THR	HB	H	4.317	1
217	1	34	THR	HG21	H	1.232	1
218	1	34	THR	HG22	H	1.232	1
219	1	34	THR	HG23	H	1.232	1
220	1	35	VAL	H	H	7.373	1
221	1	35	VAL	HA	H	3.895	1
222	1	35	VAL	HB	H	1.984	1
223	1	35	VAL	HG11	H	0.823	1
224	1	35	VAL	HG12	H	0.823	1
225	1	35	VAL	HG13	H	0.823	1
226	1	35	VAL	HG21	H	0.705	1
227	1	35	VAL	HG22	H	0.705	1
228	1	35	VAL	HG23	H	0.705	1

Release date

2023-03-29

Citation

Structure-function relationship of new peptides activating human Na(v)1.1
Lopez, L., De Waard, S., Meudal, H., Caumes, C., Khakh, K., Peigneur, S., Oliveira-Mendes, B., Lin, S., De Waele, J., Montnach, J., Cestele, S., Tessier, A., Johnson, J.P., Mantegazza, M., Tytgat, J., Cohen, C., Beroud, R., Bosmans, F., Landon, C., De Waard, M.
Biomed. Pharmacother. (2023), 165, 115173-115173, PubMed 37453200 , DOI 10.1016/j.biopha.2023.115173 , Abstract

Entries sharing articles BMRB: 5 entries Detail

  BMRB: 34791 released on 2023-09-14
    Title JzTx-34 toxin peptide H18A mutant
  BMRB: 34794 released on 2023-09-14
    Title JzTx-34 toxin peptide W31A mutant
  BMRB: 34790 released on 2023-03-29
    Title JzTx-34 toxin peptide
  BMRB: 34792 released on 2023-03-29
    Title JzTx-34 toxin peptide E20A mutant
  BMRB: 34793 released on 2023-03-29
    Title JzTx-34 toxin peptide W25A mutant

Related entities 1. Mu-theraphotoxin-Cg1a, : 1 : 6 : 103 entities Detail

Experiments performed 5 experiments Detail

#	Name	Isotope labeling	Type	Concentration
1	JzTx-34 W33A mutant (Jingzhaotoxin-34)	natural abundance		0.1 mM

#	Name	Isotope labeling	Type	Concentration
1	JzTx-34 W33A mutant (Jingzhaotoxin-34)	natural abundance		0.1 mM

#	Name	Isotope labeling	Type	Concentration
1	JzTx-34 W33A mutant (Jingzhaotoxin-34)	natural abundance		0.1 mM

#	Name	Isotope labeling	Type	Concentration
1	JzTx-34 W33A mutant (Jingzhaotoxin-34)	natural abundance		0.1 mM

#	Name	Isotope labeling	Type	Concentration
1	JzTx-34 W33A mutant (Jingzhaotoxin-34)	natural abundance		0.1 mM

nullKeywords JZTX-34 PEPTIDE TOXIN, TOXIN, hNav1.1 channel sodium channel

Search

Query history

Resources

Search for primary databases

Search for subsidiary databases

Display

Hits per page

Statistics

Query Changes will take effect after "OK" button is selected.

Maximum hits

Default conjunction operator

Omni-box

Search filter

Sequence search (BLAST)

E-value

Query sequence coverage

Miscellaneous

The number of previewed publications

Completeness of assigned chemical shift

Sequence chart about top aligned regions

Sequence chart about interacting regions

Hit context with highlight

Link destinations for BMRB, PDB and EMDB

Found 1 Document (0.825 seconds)

BMRB: 34795

Entries sharing articles BMRB: 5 entries Detail

Related entities 1. Mu-theraphotoxin-Cg1a, : 1 : 6 : 103 entities Detail

Experiments performed 5 experiments Detail

Instrument

Sample

Instrument

Sample

Instrument

Sample

Instrument

Sample

Instrument

Sample